1. Force quit any Diablo III, Agent and Blizzard Launcher processes in Activity Monitor.
2. Navigate to /Applications/Diablo III.
3. Delete the D3Debug.txt file.
4. Using Finder, navigate to the /Applications directory.
5. Right-click the game folder and select Get Info.
6. In the info box, go to the Sharing & Permissions section and click on the lock to unlock it. Enter your administrator password when prompted.
Make sure all privileges are set to Read & Write.
7. Click on the Burst icon (cogwheel) and select Apply to all enclosed items. Select Yes to confirm the action.

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Note: Step 5 must be done, even if the folder already displays Read & Write privileges. This helps ensure all enclosed files have the same permissions

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8. Launch Diablo III.
If the game prompts to enter in your administrator username/password, hit Cancel.
If it doesn't it should load fine.
9. Diablo III should load

ลองแล้ว ได้ผลครับ ^^

มาเห็นเมื่อสาย ผมลงใหม่ไปแล้วเมื่อวาน - -' install นานโคตรเกมนี้